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. 2010 Apr 7;8(7):1588-95.
doi: 10.1039/b924309g. Epub 2010 Feb 10.

The continuous flow synthesis of butane-2,3-diacetal protected building blocks using microreactors

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The continuous flow synthesis of butane-2,3-diacetal protected building blocks using microreactors

Catherine F Carter et al. Org Biomol Chem. .

Abstract

The continuous flow synthesis of butane-2,3-diacetal protected derivatives has been achieved using commercially available flow chemistry microreactors in concert with solid supported reagents and scavengers to provide in-line purification systems. The BDA protected products are all obtained in superior yield to the corresponding batch processes.

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