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Review
. 2010:664:15-9.
doi: 10.1007/978-1-4419-1399-9_2.

Regulation of angiogenesis by macrophages

Rajendra S Apte  1
Affiliations
Review

Regulation of angiogenesis by macrophages

Rajendra S Apte. Adv Exp Med Biol. 2010.

Abstract

Abnormal angiogenesis is a cardinal feature in the pathophysiology of several diseases of the retina including retinopathy of prematurity, diabetic retinopathy and choroidal neovascularization associated with age-related macular degeneration. Recent evidence has implicated macrophages as components of the innate immune system that play a key role in regulating angiogenesis in the retina and choroid. This review will focus on the role of macrophages in regulating ocular angiogenesis.

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