Lack of a relationship between colony-forming efficiency and surviving fraction at 2 Gy
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- PMID: 2023996
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Lack of a relationship between colony-forming efficiency and surviving fraction at 2 Gy
Radiat Res.
1991 May.
Abstract
The relationship between in vitro radiation sensitivity and colony-forming efficiency has been examined for primary human tumors of the cervix, colorectum, and lymph gland. Tumors were cultured using the Courtenay-Mills soft agar clonogenic assay and radiosensitivity was assessed as surviving fraction at 2 Gy. There was no correlation between colony-forming efficiency and surviving fraction at 2 Gy, giving confidence to the use of surviving fraction at 2 Gy as a predictor of clinical outcome.
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