Investigations into the effects of ACTH on the half-life of mitochondrial proteins in the rat adrenal cortex
- PMID: 202480
- DOI: 10.1007/BF01921946
Investigations into the effects of ACTH on the half-life of mitochondrial proteins in the rat adrenal cortex
Abstract
ACTH elongates the half-life of the mitochondrial proteins from the rat adrenal cortex, and chloramphenicol inhibits this effect of ACTH. The hypothesis is advanced that the ACTH-provoked stabilization of the adrenocortical mitochondrial proteins requires continuous mitochondrial DNA-dependent protein synthesis.
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