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. 1978 Jan 15;34(1):133-4.
doi: 10.1007/BF01921946.

Investigations into the effects of ACTH on the half-life of mitochondrial proteins in the rat adrenal cortex

Investigations into the effects of ACTH on the half-life of mitochondrial proteins in the rat adrenal cortex

G Neri et al. Experientia. .

Abstract

ACTH elongates the half-life of the mitochondrial proteins from the rat adrenal cortex, and chloramphenicol inhibits this effect of ACTH. The hypothesis is advanced that the ACTH-provoked stabilization of the adrenocortical mitochondrial proteins requires continuous mitochondrial DNA-dependent protein synthesis.

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