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. 1991 Feb;35(2):368-70.
doi: 10.1128/AAC.35.2.368.

Uptake of sparfloxacin and norfloxacin by clinical isolates of Staphylococcus aureus

S Yoshida  1 , T Kojima, M Inoue, S Mitsuhashi
Affiliations

Uptake of sparfloxacin and norfloxacin by clinical isolates of Staphylococcus aureus

S Yoshida et al. Antimicrob Agents Chemother. 1991 Feb.

Abstract

The amount of sparfloxacin uptake was higher than that of norfloxacin uptake in Staphylococcus aureus. Moreover, energy-dependent reduction in quinolone uptake, probably due to active efflux of the quinolone, was observed. The reduction in quinolone uptake appeared to be associated with quinolone resistance in S. aureus.

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