Uptake of sparfloxacin and norfloxacin by clinical isolates of Staphylococcus aureus
- PMID: 2024969
- PMCID: PMC245007
- DOI: 10.1128/AAC.35.2.368
Uptake of sparfloxacin and norfloxacin by clinical isolates of Staphylococcus aureus
Abstract
The amount of sparfloxacin uptake was higher than that of norfloxacin uptake in Staphylococcus aureus. Moreover, energy-dependent reduction in quinolone uptake, probably due to active efflux of the quinolone, was observed. The reduction in quinolone uptake appeared to be associated with quinolone resistance in S. aureus.
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