Comparative Study
The influence of various drugs on the binding of tianeptine to human plasma proteins
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- PMID: 2026465
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Comparative Study
The influence of various drugs on the binding of tianeptine to human plasma proteins
Int J Clin Pharmacol Ther Toxicol.
1991 Feb.
Abstract
The plasma binding of the atypical tricyclic antidepressant tianeptine was studied in combination with six drugs, at therapeutic concentrations: cyamemazine, levomepromazine, flunitrazepam, oxazepam, diclofenac and salicylic acid. Of these drugs, only salicylic acid at high plasma concentrations impaired tianeptine binding and thus may potentiate its effects.
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