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Comparative Study
. 1991 Mar;22(2):135-41.
doi: 10.1016/0163-4453(91)91525-3.

The serological diagnosis of human hydatid disease by time-resolved fluoroimmunoassay

A Aceti  1 , A Pennica, A Teggi, A Grilli, M Caferro, D Celestino, O Leri, A Sebastiani, F De Rosa
Affiliations
Comparative Study

The serological diagnosis of human hydatid disease by time-resolved fluoroimmunoassay

A Aceti et al. J Infect. 1991 Mar.

Abstract

The use of a new immunoassay, time-resolved fluoroimmunoassay (TR-FIA), in the diagnosis of human hydatid disease has been evaluated. This technique, which is based on the labelling of antibodies with europium (Eu), was compared with a well-established method, the enzyme linked immunosorbent assay (ELISA). Of 102 patients with hydatid disease, 97 (95.1%) were positive according to TR-FIA and 83 (81.4%) according to ELISA. The rate of non-specificity for other parasitic infections (n = 206) was 8.7% for TR-FIA and 17.5% for ELISA. It is concluded that TR-FIA is more sensitive and more specific than ELISA in the diagnosis of human hydatid disease.

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