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. 1991 Apr;84(4):221-3.
doi: 10.1177/014107689108400412.

Epilepsy after craniotomy and the place of prophylactic anticonvulsant drugs: discussion paper

Affiliations

Epilepsy after craniotomy and the place of prophylactic anticonvulsant drugs: discussion paper

M D Shaw et al. J R Soc Med. 1991 Apr.

Abstract

A retrospective study of 1000 patients who had undergone supratentorial neurosurgery and with prolonged follow-up revealed an overall postoperative incidence of epilepsy of 17%. The incidence varied with different pathologies but anticonvulsants given prophylactically in a randomized trial did not significantly alter the incidence. Routine anticonvulsant prophylaxis cannot be recommended.

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