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Case Reports
. 1991 May;41(5):726-9.
doi: 10.1212/wnl.41.5.726.

Disruption of human circadian and cognitive regulation following a discrete hypothalamic lesion: a case study

R A Cohen  1 , H E Albers
Affiliations
Case Reports

Disruption of human circadian and cognitive regulation following a discrete hypothalamic lesion: a case study

R A Cohen et al. Neurology. 1991 May.

Abstract

We report a patient with rostral hypothalamic damage that significantly disrupted temporal patterning of the sleep-wake cycle, body temperature, and cognitive and behavioral functioning. The findings suggest that the suprachiasmatic region of the hypothalamus is important for the circadian control of human behavior, and that circadian organization may be essential for normal cognitive functioning.

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