Guillain-Barré syndrome and influenza vaccination in the US Army, 1980-1988

Abstract

An increased incidence of Guillain-Barré syndrome (polyradiculoneuritis) occurred in individuals who received the A/New Jersey (swine) influenza vaccine in 1976-1977. A retrospective study encompassing the years 1980-1988 was conducted to determine if the US Army's mass influenza vaccination program has been associated with an increased incidence of Guillain-Barré syndrome in active duty soldiers during the study years. No temporally related increase in Guillain-Barré syndrome was found during the study years.