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. 2010 Jan;2(1):43-8.
doi: 10.4103/0974-777X.59250.

Recommendations for control of East african sleeping sickness in Uganda

Affiliations

Recommendations for control of East african sleeping sickness in Uganda

Simon Kotlyar. J Glob Infect Dis. 2010 Jan.

Abstract

East African sleeping sickness, caused by Trypanosoma brucei rhodesiense, is prominent in Uganda and poses a serious public health challenge in the region. This publication attempts to provide key components for designing a strategy for a nationwide initiative to provide insecticide-treatment of the animal reservoir to control T. b. rhodesiense. The contents of this article will focus on insecticide-based vector control strategies, monitoring and evaluation framework, and knowledge gaps required for future initiatives.

Keywords: East African sleeping sickness; animal reservoir; insecticide-treatment; monitoring and evaluation.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
New T. b. rhodesiense cases reported to WHO, Uganda 1997-2006. (WHO 2007)
Figure 2
Figure 2
Experimental model for reduction of reproductive rate (R0) for case treatment vs. livestock chemoprophylaxis. T.b.r = Trypanosoma brucei rhodesiensse. T.b.g. = Trypanosoma brucei gambiense. Adapted from Welburn et al. 2001.
Figure 3
Figure 3
Average annual incidence of sleeping sickness by sub-county, 1998-2003. Berrang-Ford et. al. 2006

References

    1. Berrang-Ford L, Berke O, Abdelrahman L, Waltner-Toews D, McDermott J. Spatial analysis of sleeping sickness, southeastern Uganda, 1970-2003. Emerg Infect Dis. 2006;12:813–20. - PMC - PubMed
    1. Fèvre EM, Coleman PG, Odiit M, Magona JW, Welburn SC, Woolhouse ME. The origins of a new Trypanosoma brucei rhodesiense sleeping sickness outbreak in eastern Uganda. Lancet. 2001;358:625–8. - PubMed
    1. Welburn SC, Coleman PG, Maudlin I, Fèvre EM, Odiit M, Eisler MCCrisis. Control of Rhodesian sleeping sickness? Trends Parasitol. 2006;22:123–8. what crisis? - PubMed
    1. Welburn SC, Fèvre EM, Coleman PG, Odiit M, Maudlin I. Sleeping sickness: a tale of two diseases. Trends Parasitol. 2001;17:19–24. - PubMed
    1. Zoller T, Fèvre EM, Welburn SC, Odiit M, Coleman PG. Analysis of risk factors for T. brucei rhodesiense sleeping sickness within villages in south-east Uganda. BMC Infect Dis. 2008;8:88. - PMC - PubMed