Biological Roles of Glycans
- PMID: 20301233
- Bookshelf ID: NBK1897
Biological Roles of Glycans
Excerpt
This chapter provides an overview of the biological roles of glycans and attempts to synthesize some general principles for understanding and exploring these roles. For details, see the reviews cited and the other chapters in this book.
Copyright © 2009, The Consortium of Glycobiology Editors, La Jolla, California.
Sections
- GENERAL PRINCIPLES
- BIOLOGICAL CONSEQUENCES OF ALTERING GLYCOSYLATION ARE VARIABLE
- STRUCTURAL AND MODULATORY ROLES OF GLYCANS
- GLYCANS AS SPECIFIC LIGANDS FOR CELL–CELL INTERACTIONS (INTRINSIC RECOGNITION)
- GLYCANS AS SPECIFIC LIGANDS FOR CELL–MICROBE INTERACTIONS (EXTRINSIC RECOGNITION)
- MOLECULAR MIMICRY OF HOST GLYCANS BY PATHOGENS
- THE SAME GLYCAN CAN HAVE DIFFERENT ROLES WITHIN AN ORGANISM
- INTRASPECIES AND INTERSPECIES VARIATIONS IN GLYCOSYLATION
- IMPORTANCE OF TERMINAL SEQUENCES, MODIFICATIONS, AND UNUSUAL STRUCTURES
- ARE THERE “JUNK” GLYCANS?
- APPROACHES TO ELUCIDATING SPECIFIC BIOLOGICAL ROLES OF GLYCANS
- FURTHER READING
References
-
- Roseman S. The synthesis of carbohydrates by multiglycosyltransferase systems and their potential function in intercellular adhesion. Chem Phys Lipids. 1970;5:270–297. - PubMed
-
- Montreuil J. Primary structure of glycoprotein glycans: Basis for the molecular biology of glycoproteins. Adv. Carbohydr. Chem. Biochem. 1980;37:157–223. - PubMed
-
- Berger EG, Buddecke E, Kamerling JP, Kobata A, Paulson JC, Vliegenthart JFG. Structure, biosynthesis and functions of glycoprotein glycans. Experientia. 1982;38:1129–1162. - PubMed
-
- Rademacher TW, Parekh RB, Dwek RA. Glycobiology. Annu. Rev. Biochem. 1988;57:785–838. - PubMed
-
- Hart GW. Glycosylation. Curr. Opin. Cell. Biol. 1992;4:1017–1023. - PubMed
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