Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review

Proteoglycans and Sulfated Glycosaminoglycans

Jeffrey D Esko, Koji Kimata, Ulf Lindahl
Ajit Varki, Richard D Cummings, Jeffrey D Esko, Hudson H Freeze, Pamela Stanley, Carolyn R Bertozzi, Gerald W Hart, Marilynn E Etzler
, editors.
In: Essentials of Glycobiology. 2nd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009. Chapter 16.
Free Books & Documents
Review

Proteoglycans and Sulfated Glycosaminoglycans

Jeffrey D Esko et al.
Free Books & Documents

Excerpt

This chapter focuses on the structure, biosynthesis, and general biology of proteoglycans. Topics include a description of the major families of proteoglycans, their characteristic polysaccharide chains (glycosaminoglycans), biosynthetic pathways, and general concepts about proteoglycan function. Proteoglycans, like other glycoconjugates, are enormously diverse and have many essential roles in biology.

PubMed Disclaimer

References

    1. Bernfield M, Gotte M, Park PW, Reizes O, Fitzgerald ML, Lincecum J, Zako M. Functions of cell surface heparan sulfate proteoglycans. Annu Rev Biochem. 1999;68:729–777. - PubMed
    1. Lindahl U. What else can “heparin” do? Haemostasis. 1999;29:38–47. - PubMed
    1. Yamaguchi Y. Lecticans: Organizers of the brain extracellular matrix. Cell Mol Life Sci. 2000;57:276–289. - PubMed
    1. Gallagher JT. Heparan sulfate: Growth control with a restricted sequence menu. J Clin Invest. 2001;108:357–361. - PMC - PubMed
    1. Esko JD, Selleck SB. Order out of chaos: Assembly of ligand binding sites in heparan sulfate. Annu Rev Biochem. 2002;71:435–471. - PubMed

LinkOut - more resources