Sialic Acids
- PMID: 20301246
- Bookshelf ID: NBK1920
Sialic Acids
Excerpt
This chapter describes the sialic acid family of monosaccharides , with respect to their biosynthesis, structural diversity, and linkage to the underlying glycan chain. Also mentioned are the general principles behind different methods for their study. The biological and pathophysiological roles of sialic acids are briefly considered, particularly the functional significance of lectins that recognize sialic acids.
Copyright © 2009, The Consortium of Glycobiology Editors, La Jolla, California.
Sections
- HISTORICAL BACKGROUND
- DIVERSITY IN STRUCTURE AND LINKAGE
- THE EXTENDED 2-KETO-3-DEOXYNONONIC ACID FAMILY
- NOMENCLATURE AND ABBREVIATIONS
- OLIGOSIALIC AND POLYSIALIC ACIDS
- TISSUE- AND MOLECULE-SPECIFIC EXPRESSION OF LINKAGES AND MODIFICATIONS
- METABOLISM
- METHODS FOR STUDYING SIALIC ACIDS
- GENERAL FUNCTIONS OF SIALIC ACIDS
- SIALIC-ACID-RECOGNIZING LECTINS
- PRACTICAL USES OF SIALIC-ACID-BINDING LECTINS
- EVOLUTIONARY HISTORY OF SIALIC ACIDS
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LOSS OF
N -GLYCOLYLNEURAMINIC ACID PRODUCTION IN HUMANS - SIALIC ACIDS IN DEVELOPMENT AND MALIGNANCY
- SIALIC ACIDS IN PATHOLOGY AND PHARMACOLOGY
- FURTHER READING
References
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