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Review

R-type Lectins

Richard D Cummings, Marilynn E Etzler
Ajit Varki, Richard D Cummings, Jeffrey D Esko, Hudson H Freeze, Pamela Stanley, Carolyn R Bertozzi, Gerald W Hart, Marilynn E Etzler
, editors.
In: Essentials of Glycobiology. 2nd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009. Chapter 28.
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Review

R-type Lectins

Richard D Cummings et al.
Free Books & Documents

Excerpt

The R-type lectins are members of a superfamily of proteins, all of which contain a carbohydrate-recognition domain (CRD) that is structurally similar to the CRD in ricin. Ricin was the first lectin discovered and it is the prototypical lectin in this category. R-type lectins are present in plants, animals, and bacteria, and the plant lectins often contain a separate subunit that is a potent toxin. The structure–function relationships of this group of proteins are discussed in this chapter.

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References

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