Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2010 Mar 19:8:16.
doi: 10.1186/1477-7819-8-16.

A case of high-grade leiomyosarcoma of the bladder with delayed onset and very poor prognosis

Enzo Ricciardi  1 , Paolo Maniglio, Mauro Schimberni, Massimo Moscarini
Affiliations
Case Reports

A case of high-grade leiomyosarcoma of the bladder with delayed onset and very poor prognosis

Enzo Ricciardi et al. World J Surg Oncol. .

Abstract

Mesenchymal tumors represent a small number of bladder cancer cases. Leiomyosarcoma is the most common histology with over 100 cases reported in the whole literature. This tumor is been historically considered as highly aggressive and showing a poor prognosis. Despite very low survival rates showed in older reports, some authors indicate that some patients could have a better outcome. We report a review of the literature and a case of high-grade LMS of the bladder in a 68 years old woman. Diagnosis was delayed and disease was locally advanced. Symptoms and imaging of our case first oriented to a gynecologic condition with an adnexal or uterine origin of the mass, and, a genitourinary origin could be unveiled only intra-operatively.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Leiomyosarcoma of the bladder (Hematoxylin and eosin).
Figure 2
Figure 2
Leiomyosarcoma of the bladder (Smooth muscle actin).
Figure 3
Figure 3
Leiomyosarcoma of the bladder (Ki67).
See this image and copyright information in PMC

References

    1. Pedersen-Bjergaard J, Jonsson V, Pedersen M, Hou-Jensen K. Leiomyosarcoma of the urinary bladder after cyclophosphamide. J Clin Oncol. 1995;13:532–3. - PubMed
    1. Parekh DJ, Jung C, O'Conner J, Dutta S, Smith ER Jr. Leiomyosarcoma in urinary bladder after cyclophosphamide therapy for retinoblastoma and review of bladder sarcomas. Urology. 2002;60:164. doi: 10.1016/S0090-4295(02)01701-6. - DOI - PubMed
    1. Berkmen F, Celebioglu AS. Adult genitourinary sarcomas: a report of seventeen cases and review of the literature. J Exp Clin Cancer Res. 1997;16:45–48. - PubMed
    1. Dahm P, Gschwend JE. Malignant non-urothelial neoplasms of the urinary bladder: a review. Eur Urol. 2003;44:672–681. doi: 10.1016/S0302-2838(03)00416-0. - DOI - PubMed
    1. Seo IS, Clark SA, McGovern FD, Clark DL, Johnson EH. Leiomyosarcoma of the urinary bladder: 13 years after cyclophosphamide therapy for Hodgkin's disease. Cancer. 1985;55:1597–1603. doi: 10.1002/1097-0142(19850401)55:7<1597::AID-CNCR2820550731>3.0.CO;2-0. - DOI - PubMed

Publication types