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. 2010 May-Jun;50(5-6):223-9.
doi: 10.1016/j.ypmed.2010.03.007. Epub 2010 Mar 18.

Predictors of reported influenza vaccination in HIV-infected women in the United States, 2006-2007 and 2007-2008 seasons

Keri N Althoff  1 , Kathryn Anastos, Kenrad E Nelson, David D Celentano, Gerald B Sharp, Ruth M Greenblatt, Audrey L French, Don J Diamond, Susan Holman, Mary Young, Stephen J Gange
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Predictors of reported influenza vaccination in HIV-infected women in the United States, 2006-2007 and 2007-2008 seasons

Keri N Althoff et al. Prev Med. 2010 May-Jun.

Abstract

Objective: To estimate the cumulative incidence of self-reported influenza vaccination ("vaccination coverage") and investigate predictors in HIV-infected women.

Methods: In an ongoing cohort study of HIV-infected women in five US cities, data from two influenza seasons (2006-2007 n=1209 and 2007-2008 n=1161) were used to estimate crude and adjusted prevalence ratios (aPR) and 95% confidence intervals ([,]) from Poisson regression with robust variance models using generalized estimating equations (GEE).

Results: In our study, 55% and 57% of HIV-infected women reported vaccination during the 2006-2007 and 2007-2008 seasons, respectively. Using data from both seasons, older age, non-smoking status, CD4 T-lymphocyte (CD4) count > or =200 cells/mm(3), and reporting at least one recent healthcare visit was associated with increased vaccination coverage. In the 2007-2008 season, a belief in the protection of the vaccine (aPR=1.38 [1.18, 1.61]) and influenza vaccination in the previous season (aPR=1.66 [1.44, 1.91]) most strongly predicted vaccination status.

Conclusion: Interventions to reach unvaccinated HIV-infected women should focus on changing beliefs about the effectiveness of influenza vaccination and target younger women, current smokers, those without recent healthcare visits, or a CD4 count <200 cells/mm(3).

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Figure 1
Figure 1
Month of influenza vaccination reported by HIV-infected women in the Women’s Interagency HIV Study, 2006-07 (n=1,209) and 2007-08 (n=1,161) influenza seasons, United States
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