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Comment
. 2010 Mar 16;107(11):E38-9; author reply e40-1.
doi: 10.1073/pnas.0915120107.

Revision of the mtDNA tree and corresponding haplogroup nomenclature

Mannis van Oven
Comment

Revision of the mtDNA tree and corresponding haplogroup nomenclature

Mannis van Oven. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Revised mtDNA phylogeny with newly proposed haplogroup nomenclature based on 78 complete mtDNA sequences. The 25 sequences in boxes are from Zhao et al. (2). Mutations are transitions unless an exact base change is specified; R or Y indicate heteroplasmic states. Insertions and deletions are indicated with + and d, respectively. C insertions at positions 309 and 315, deletions of an AC dinucleotide at positions 523–524, and transitions at position 16519 were omitted. Homoplasic mutations are underlined only when they are recurrent within one of the clades A, M12’G, M13’46’61, M40’62, or M9. In the case that they are back mutations of an ancestral mutation, they are preceded by @. Age estimates for haplogroups (± SE intervals) were calculated using entire genome substitutions according to ref. . Sample names refer to the sources Bilal et al. (6), Chandrasekar et al. (5), Dancause et al. (7), Fornarino et al. (8), Hartmann et al. (3), Herrnstadt et al. (9), Ingman et al. (10), Kong et al. (11), Macaulay et al. (12), Soares et al. (13), Tanaka et al. (14), Ueno et al. (15), and Zhao et al. (2), and they can be looked up in GenBank through their respective accession numbers.
See this image and copyright information in PMC

Comment on

References

    1. van Oven M, Kayser M. Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Hum Mutat. 2009;30:E386–E394. - PubMed
    1. Zhao M, et al. Mitochondrial genome evidence reveals successful Late Paleolithic settlement on the Tibetan Plateau. Proc Natl Acad Sci USA. 2009;106:21230–21235. - PMC - PubMed
    1. Hartmann A, et al. Validation of microarray-based resequencing of 93 worldwide mitochondrial genomes. Hum Mutat. 2009;30:115–122. - PubMed
    1. Soares P, et al. Correcting for purifying selection: An improved human mitochondrial molecular clock. Am J Hum Genet. 2009;84:740–759. - PMC - PubMed
    1. Chandrasekar A, et al. Updating phylogeny of mitochondrial DNA macrohaplogroup m in India: Dispersal of modern human in South Asian corridor. PLoS One. 2009;4:e7447. - PMC - PubMed

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