Elevation of serum progesterone with oral micronized progesterone after in vitro fertilization. A randomized, controlled trial
- PMID: 2030491
Elevation of serum progesterone with oral micronized progesterone after in vitro fertilization. A randomized, controlled trial
Abstract
In a randomized, controlled trial, oral micronized progesterone (P4) supplementation effectively elevated luteal phase serum P4 levels after in vitro fertilization (IVF). Of 34 nonconception IVF cycles, 12 were supplemented with oral micronized P4, 200 mg four times daily, beginning the day of oocyte retrieval, while 22 control cycles did not receive supplementation. With oral micronized P4 supplementation the P4 levels were higher (P less than .001) and the luteal phase longer (P less than .05). Oral micronized P4 supplementation appears to be a convenient method of supporting serum P4 levels during the luteal phase after IVF.
Similar articles
-
Effects of early luteal-phase vaginal progesterone supplementation on the outcome of in vitro fertilization and embryo transfer.Gynecol Endocrinol. 2008 Dec;24(12):674-80. doi: 10.1080/09513590802360751. Gynecol Endocrinol. 2008. PMID: 19172535 Clinical Trial.
-
Estradiol supplementation during the luteal phase of IVF-ICSI patients: a randomized, controlled trial.Fertil Steril. 2008 Dec;90(6):2190-5. doi: 10.1016/j.fertnstert.2007.10.021. Epub 2008 Jan 14. Fertil Steril. 2008. PMID: 18191847 Clinical Trial.
-
Early luteal progesterone supplementation during in vitro fertilization cycles. A randomized trial.J Reprod Med. 1992 Mar;37(3):210-4. J Reprod Med. 1992. PMID: 1564703 Clinical Trial.
-
An update of luteal phase support in stimulated IVF cycles.Hum Reprod Update. 2007 Nov-Dec;13(6):581-90. doi: 10.1093/humupd/dmm021. Epub 2007 Jul 11. Hum Reprod Update. 2007. PMID: 17626114 Review.
-
Luteal supplementation in in vitro fertilization: more questions than answers.Fertil Steril. 2008 Apr;89(4):749-58. doi: 10.1016/j.fertnstert.2008.02.095. Fertil Steril. 2008. PMID: 18406833 Review.
Cited by
-
A review of conventional and sustained-release formulations of oral natural micronized progesterone in obstetric indications.Drugs Context. 2021 Oct 13;10:2021-7-1. doi: 10.7573/dic.2021-7-1. eCollection 2021. Drugs Context. 2021. PMID: 34721615 Free PMC article. Review.
-
Luteal phase support for assisted reproduction cycles.Cochrane Database Syst Rev. 2015 Jul 7;2015(7):CD009154. doi: 10.1002/14651858.CD009154.pub3. Cochrane Database Syst Rev. 2015. PMID: 26148507 Free PMC article.