Cytoprotective activity of pectic polysaccharides from the root of panax ginseng
- PMID: 2030589
- DOI: 10.1016/0378-8741(91)90148-7
Cytoprotective activity of pectic polysaccharides from the root of panax ginseng
Abstract
An acidic polysaccharide fraction, GRA-4, of the root extract of Panax ginseng, when administered from 50 to 200 mg/kg orally, inhibited gastric lesions induced by HCl-ethanol or absolute ethanol, in a dose-dependent manner. The cytoprotective activity of GRA-4 decreased after its treatment with periodate but not after protein digestion, indicating that the carbohydrate moiety of this acidic polysaccharide contributes to this activity.
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