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. 2010 Aug;41(1):1-4.
doi: 10.1007/s11262-010-0472-9. Epub 2010 Mar 20.

Genetic analysis of the VP1 region of enterovirus 71 reveals the emergence of genotype A in central China in 2008

Haiyang Yu  1 , Wei Chen, Hongwei Chang, Renshu Tang, Jun Zhao, Lin Gan, Boyu Liu, Jason Chen, Mingli Wang
Affiliations

Genetic analysis of the VP1 region of enterovirus 71 reveals the emergence of genotype A in central China in 2008

Haiyang Yu et al. Virus Genes. 2010 Aug.

Abstract

Enterovirus 71 (EV71) strains from children were characterized by full-length VP1 nucleotide sequencing. Out of 22 clinical specimens, five isolates identified as EV71 were recovered by virus isolation. The VP1 sequences of the five isolates had more than 97.4% sequence identity with prototype virus BrCr, clustering in the genotype A lineage. This represents the first record of genotype A EV71 in China since the BrCr prototype strain was discovered in the USA in 1969.

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