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. 1991 Feb;37(2):56-8.

[Results of the toxicokinetics of bromoxynil in rats]

[Article in German]
M Stähler  1 , S Gericke, H Beitz
Affiliations
  • PMID: 2031382

[Results of the toxicokinetics of bromoxynil in rats]

[Article in German]
M Stähler et al. Z Gesamte Hyg. 1991 Feb.

Abstract

The present paper reports on toxicokinetics of bromoxynil after oral administration of two different dosages in male and female rats. The concentrations measured in serum proceed with a terminal half life of 20 h. Differences in sex are expressed in MRT- and AUC-values. The simulated concentration course after multiple dosing corresponds essentially to experimental course (male rats). Toxicokinetics studies of liver and kidney show a saturation kinetics in kidney after oral administration of a high dose (100 mg/kg KM) in case female rats.

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