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Review
. 1976;47(4):323-33.

Cellular action of gastrointestinal polypeptide hormones

J Borsy, F Andrási, E Kósa
  • PMID: 203165
Review

Cellular action of gastrointestinal polypeptide hormones

J Borsy et al. Acta Physiol Acad Sci Hung. 1976.

Abstract

The present state of chemistry, structure-activity relationship and cellular mode of action of gastrointestinal polypeptide hormones (gastrin, secretin, cholecystokinin-pancreozymin, caerulein and bombesin) are reviewed. Possible structure of polypeptide receptors and the mechanism of peptide--receptor interaction are described, and the role of acetylcholine and histamine in secretion discussed. The present data support the hormonal-receptor significance of cyclic nucleotides (cAMP, cGMP) in the cellular regulation of secretion.

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