Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2010 Jan-Feb;81(1):28-40.
doi: 10.1111/j.1467-8624.2009.01380.x.

How the timing and quality of early experiences influence the development of brain architecture

Sharon E Fox  1 , Pat Levitt, Charles A Nelson 3rd
Affiliations
Review

How the timing and quality of early experiences influence the development of brain architecture

Sharon E Fox et al. Child Dev. 2010 Jan-Feb.

Abstract

Early life events can exert a powerful influence on both the pattern of brain architecture and behavioral development. In this study a conceptual framework is provided for considering how the structure of early experience gets "under the skin." The study begins with a description of the genetic framework that lays the foundation for brain development, and then proceeds to the ways experience interacts with and modifies the structures and functions of the developing brain. Much of the attention is focused on early experience and sensitive periods, although it is made clear that later experience also plays an important role in maintaining and elaborating this early wiring diagram, which is critical to establishing a solid footing for development beyond the early years.

PubMed Disclaimer

References

    1. Akahane-Yamada R, Strange W, Downs-Pruitt JC, Masuda Y. Modification of L2 vowel production by intensive perception training as evaluated by acoustic analysis and native speakers. Journal of the Acoustical Society of America. 1998;103:3089–3096.
    1. Akins MR, Biederer T. Cell-cell interactions in synaptogenesis. Current Opinion in Neurobiology. 2006;16:83–89. - PubMed
    1. Alcamo EA, Chiriella L, Dautzenberg M, Dobreva G, Farinas I, Grosschedl R, et al. Satb2 regulates callosal projection neuron identity in the developing cerebral cortex. Neuron. 2008;57:364–377. - PubMed
    1. Amedi A, Stern WM, Camprodon JA, Bermpohl F, Merabet L, Rotman S, et al. Shape conveyed by visual-to-auditory sensory substitution activates the lateral occipital complex. Nature Neuroscience. 2007;10:687–689. - PubMed
    1. Anisman H, Zaharia MD, Meaney MJ, Merali Z. Do early-life events permanently alter behavioral and hormonal responses to stressors? International Journal of Developmental Neuroscience. 1998;16:149–164. - PubMed

Publication types