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Review
. 2010 Apr;3(4):416-9.
doi: 10.1158/1940-6207.CAPR-10-0045. Epub 2010 Mar 23.

Interphase cytogenetics of sputum cells for the early detection of lung carcinogenesis

Sheila A Prindiville  1 , Thomas Ried
Affiliations
Review

Interphase cytogenetics of sputum cells for the early detection of lung carcinogenesis

Sheila A Prindiville et al. Cancer Prev Res (Phila). 2010 Apr.

Abstract

This perspective on Varella-Garcia et al. (beginning on p. 447 in this issue of the journal) examines the role of interphase fluorescence in situ hybridization for the early detection of lung cancer. This work is an important step toward identifying and validating a molecular marker in sputum samples for lung cancer early detection and highlights the value of establishing cohort studies with biorepositories of samples collected from participants followed over time for disease development.

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Conflict of interest statement

Disclosure of Potential Conflicts of Interest: No potential conflicts of interest were disclosed.

Comment on

References

    1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin. 2009;59:225–49. - PubMed
    1. Horner MJ, Ries LAG, Krapcho M, et al. Bethesda, MD: National Cancer Institute; 2010. SEER Cancer Statistics Review, 1975-2006. http://seer.cancer.gov/csr/1975_2006/ based on November 2008 SEER data submission, posted to the SEER web site.
    1. Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A, editors. AJCC Cancer Staging Manual. New York: Springer; 2010. Lung and Bronchus.
    1. Saccomanno G, Saunders RP, Ellis H, Archer VE, Wood BG, Beckler PA. Concentration of carcinoma or atypical cells in sputum. Acta Cytol. 1963;7:305–10. - PubMed
    1. Saccomanno G, Archer VE, Auerbach O, Saunders RP, Brennan LM. Development of carcinoma of the lung as reflected in exfoliated cells. Cancer. 1974;33:256–70. - PubMed

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