Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Apr;89(4):1015-21; discussion 1022-3.
doi: 10.1016/j.athoracsur.2009.10.052.

Outcomes after esophagectomy in patients with prior antireflux or hiatal hernia surgery

Affiliations

Outcomes after esophagectomy in patients with prior antireflux or hiatal hernia surgery

Andrew C Chang et al. Ann Thorac Surg. 2010 Apr.

Abstract

Background: Esophagectomy is indicated occasionally for the treatment of patients with refractory gastroesophageal reflux disease (GERD) or recurrent hiatus hernia. The purpose of this study was to evaluate the impact of previous gastroesophageal operations on outcomes after esophagectomy for recurrent GERD or hiatus hernia.

Methods: Using a prospectively accumulated database, a retrospective review was performed to identify patients undergoing esophagectomy for complicated GERD or hiatus hernia. Mortality, perioperative and functional outcomes, and need for reoperation were evaluated, assessing esophagectomy patients who had undergone prior operations for GERD or hiatus hernia.

Results: Of 258 patients with GERD or hiatus hernia undergoing esophagectomy, 104 had undergone a previous operation, with a median interval to esophagectomy of 28 months. Transhiatal resection was accomplished in fewer patients undergoing reoperation (87 of 104 versus 151 of 154; p<0.005). A gastric conduit was used as an esophageal replacement in fewer patients with previous operation(s) (89 of 104 versus 150 of 154; p<0.005). Esophagectomy patients with a history of prior gastroesophageal surgery, as compared with those without, sustained more blood loss and were more likely to require reoperation, and fewer reported good to excellent swallowing function (p<0.05). There was no difference in the occurrence of anastomotic leak.

Conclusions: Esophagectomy in patients who have undergone prior operations for either GERD or hiatus hernia can be accomplished without thoracotomy and with satisfactory intermediate-term quality of life. Such patients should be evaluated and prepared for the use of alternative conduits should the remobilized stomach prove to be an unsatisfactory esophageal substitute at the time of esophagectomy.

PubMed Disclaimer

Figures

Fig 1
Fig 1
Average number of cumulative esophagoenteric anastomotic dilatations required after esophagectomy, stratified by history of prior operation and by anastomotic technique, hand-sewn or side-to-side stapled.

References

    1. Stein HJ, Feussner H, Siewert JR. Failure of antireflux surgery: causes and management strategies. Am J Surg. 1996;171:36–40. - PubMed
    1. Morgenthal C, Shane M, Stival A, et al. The durability of laparoscopic Nissen fundoplication: 11-year outcomes. J Gastrointest Surg. 2007;11:693–700. - PubMed
    1. Zaninotto G, Portale G, Costantini M, et al. Long-term results (6–10 years) of laparoscopic fundoplication. J Gastrointest Surg. 2007;11:1138–45. - PubMed
    1. Pierre AF, Luketich JD, Fernando HC, et al. Results of laparoscopic repair of giant paraesophageal hernias: 200 consecutive patients. Ann Thorac Surg. 2002;74:1909–16. - PubMed
    1. Patel HJ, Tan BB, Yee J, Orringer MB, Iannettoni MD. A twenty-five year experience with open primary transthoracic repair of paraesophageal hiatal hernia. J Thorac Cardiovasc Surg. 2004;127:843–9. - PubMed

Publication types