[Prevention of preeclampsia]

Abstract

Aspirin has shown efficacy in preventing PE with a 10 % incidence reduction. The treatment must be started between the 12(th) and 14(th) week of amenorrhea with a dose of 75 to 160 mg once daily. This treatment is all the more effective as it is given to a high risk population. The supplementation with 1,5 g of calcium per day appears effective as well in the prevention of PE, especially in the malnourished and young patents. Insufficient data is currently available to recommend antioxidant supplementation. Low molecular weight heparin is potentially beneficial in the prevention of PE, however its efficacy remains to be demonstrated and indications determined. Nitric oxide (NO) or NO releasers are not effective and can cause headaches. Diuretics reduce the birth weight without improving the incidence of PE.