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. 2009 Sep;21(3):113-5.
doi: 10.4314/mmj.v21i3.45631.

History of rotavirus research in children in Malawi: the pursuit of a killer

Nigel Cunliffe  1 , Desiree Wittel, Bagrey Ngwira
Affiliations

History of rotavirus research in children in Malawi: the pursuit of a killer

Nigel Cunliffe et al. Malawi Med J. 2009 Sep.

Abstract

Rotavirus gastroenteritis is a major health problem among Malawian children. Studies spanning 20 years have described the importance, epidemiology and viral characteristics of rotavirus infections in the country. Despite a wide diversity of circulating rotavirus strains causing severe disease in young infants, a clinical trial of a human rotavirus vaccine clearly demonstrated the potential for rotavirus vaccination to greatly reduce the morbidity and mortality due to rotavirus diarrhoea in Malawi. This new enteric vaccine initiative represents a major opportunity to improve the health and survival of Malawian children.

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References

    1. World Health Organization, author. Rotavirus vaccines. Wkly Epidemiol Rec. 2007;82:285–296. - PubMed
    1. Cunliffe NA. Viral gastroenteritis in children with and without HIV infection in Blantyre, Malawi. University of Liverpool; 2001. PhD thesis.
    1. Pavone R, Schinaia N, Hart CA, Getty B, Molyneux M, Borgstein A. Viral gastro-enteritis in children in Malawi. Ann Trop Paed. 1990;10:15–20. - PubMed
    1. Cunliffe NA, Bresee JS, Gondwe J, Hart CA. The epidemiology of diarrhoeal disease in children at Queen Elizabeth Central Hospital, Blantyre, Malawi, 1994–1997. Mai Med J. 1998;11:21–25.
    1. Cunliffe NA, Gondwe JS, Kirkwood CD, et al. Effect of concomitant HIV infection on presentation and outcome of rotavirus gastroenteritis in Malawian children. Lancet. 2001;358:550–555. - PubMed

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