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Comment
. 2010 Mar 26;32(3):296-8.
doi: 10.1016/j.immuni.2010.03.011.

Seq-ing LPS-induced enhancers

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Seq-ing LPS-induced enhancers

Stephen T Smale. Immunity. .
Free article

Abstract

In this issue of Immunity, Ghisletti et al. (2010) examined lipopolysaccharide (LPS)-induced binding of the p300 transcription coactivator to identify inducible enhancers throughout the genome of mouse macrophages, thereby revealing common features of enhancers that contribute to the LPS response and a critical role for PU.1 in enhancer marking.

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