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Review
. 2010 May;22(4):289-93.
doi: 10.1016/j.clon.2010.02.011. Epub 2010 Mar 26.

Review of testing and use of adjuvant trastuzumab across a cancer network--are we treating the right patients?

S G Coulson  1 , V S Kumar, I M Manifold, M Q Hatton, S Ramakrishnan, K S Dunn, O P Purohit, C Bridgewater, R E Coleman
Affiliations
Review

Review of testing and use of adjuvant trastuzumab across a cancer network--are we treating the right patients?

S G Coulson et al. Clin Oncol (R Coll Radiol). 2010 May.

Abstract

This review of practice assessed all early breast cancer patients diagnosed over 12 months to determine the frequency of human epidermal growth factor receptor 2 (HER2) positivity and trastuzumab use. The frequency of HER2 positivity in routine practice (185/1319; 14%) was less than expected. A significant proportion of patients (56/185; 30%) did not receive trastuzumab, largely due to concerns about chemotherapy tolerability.

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