doi: 10.1007/BF01944662.
Effect of low density lipoprotein on proteoglycan synthesis by aorta cells in culture
- PMID: 203474
- DOI: 10.1007/BF01944662
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Effect of low density lipoprotein on proteoglycan synthesis by aorta cells in culture
Experientia.
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Abstract
Increasing the content of human serum low density lipoprotein in the growth medium led to greater incorporation of 35S-sulfate into proteoglycan (mostly into dermatan sulfate) by primary aorta cells but did not affect similar incorporation by fibroblast cells. These results suggest a mechanism which can explain the increased deposition of lipid in aorta due to hyperlipidemia.
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