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Comment
. 2010 Mar 26;37(6):747-8.
doi: 10.1016/j.molcel.2010.02.016.

Avoiding a fatal attraction: properties of nucleosomes and a histone chaperone revealed under physiological conditions

Tim Formosa  1
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Avoiding a fatal attraction: properties of nucleosomes and a histone chaperone revealed under physiological conditions

Tim Formosa. Mol Cell. .
Free article

Abstract

Andrews et al. report a comprehensive thermodynamic analysis of nucleosomes in low salt, providing new insights into chromatin assembly and revealing an unexpected mechanism used by the histone chaperone Nap1 to prevent aberrant chromatin formation in vitro and in vivo.

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