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Case Reports
. 2010 Apr;82(4):563-5.
doi: 10.4269/ajtmh.2010.09-0744.

Severe congenital malaria acquired in utero

Jeanne R Poespoprodjo  1 , Afdal Hasanuddin, Wendelina Fobia, Paulus Sugiarto, Enny Kenangalem, Daniel A Lampah, Emiliana Tjitra, Ric N Price, Nicholas M Anstey
Affiliations
Case Reports

Severe congenital malaria acquired in utero

Jeanne R Poespoprodjo et al. Am J Trop Med Hyg. 2010 Apr.

Abstract

Vertical transmission of Plasmodium falciparum is under-recognized and usually associated with asymptomatic low-level parasitemia at birth. We report symptomatic congenital malaria presenting as a neonatal sepsis syndrome. The presence at birth of a high asexual parasitemia, gametocytemia, and splenomegaly indicated in utero rather than intrapartum transmission. The neonate was successfully treated with intravenous artesunate followed by oral dihydroartemisinin-piperaquine, without apparent adverse effects.

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