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Comment
. 2010 Apr;42(4):282-4.
doi: 10.1038/ng0410-282.

Epigenetic marks identify functional elements

Randall H Morse
Comment

Epigenetic marks identify functional elements

Randall H Morse. Nat Genet. 2010 Apr.

Abstract

Enhancers and transcription factor binding sites that control cell-specific transcription in higher eukaryotes can be found up to hundreds of kilobases from the promoters that they control, making their identification challenging. A new study uses a model based on histone modifications and chromatin dynamics to predict functional elements involved in androgen receptor response.

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Comment on

  • Nucleosome dynamics define transcriptional enhancers.
    He HH, Meyer CA, Shin H, Bailey ST, Wei G, Wang Q, Zhang Y, Xu K, Ni M, Lupien M, Mieczkowski P, Lieb JD, Zhao K, Brown M, Liu XS. He HH, et al. Nat Genet. 2010 Apr;42(4):343-7. doi: 10.1038/ng.545. Epub 2010 Mar 7. Nat Genet. 2010. PMID: 20208536 Free PMC article.

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