STRIDE--An integrated standards-based translational research informatics platform
- PMID: 20351886
- PMCID: PMC2815452
STRIDE--An integrated standards-based translational research informatics platform
Abstract
STRIDE (Stanford Translational Research Integrated Database Environment) is a research and development project at Stanford University to create a standards-based informatics platform supporting clinical and translational research. STRIDE consists of three integrated components: a clinical data warehouse, based on the HL7 Reference Information Model (RIM), containing clinical information on over 1.3 million pediatric and adult patients cared for at Stanford University Medical Center since 1995; an application development framework for building research data management applications on the STRIDE platform and a biospecimen data management system. STRIDE's semantic model uses standardized terminologies, such as SNOMED, RxNorm, ICD and CPT, to represent important biomedical concepts and their relationships. The system is in daily use at Stanford and is an important component of Stanford University's CTSA (Clinical and Translational Science Award) Informatics Program.
Figures
References
-
- Zerhouni EA. US biomedical research: Basic, translational, and clinical sciences. JAMA. 2005 Sep 21;294(11):1352–8. - PubMed
-
- Sung NS, Crowley WF, Genel M, Salber P, Sandy L, Sherwood LM, et al. Central challenges facing the national clinical research enterprise. JAMA. 2003;289(10):1278–87. - PubMed
-
- Payne PR, Johnson SB, Starren JB, Tilson HH, Dowdy D. Breaking the translational barriers: The value of integrating biomedical informatics and translational research. Journal of Investigative Medicine. 2005;53(4):192–200. - PubMed
-
- DiLaura R, Turisco F, McGrew C, Reel S, Glaser J, Crowley WF. Use of informatics and information technologies in the clinical research enterprise within US academic medical centers: Progress and challenges from 2005 to 2007. J Investig Med. 2008 Jun;56(5):770–9. - PubMed
-
- Williams RL, Johnson SB, Greene SM, Larson EB, Green LA, Morris A, et al. Signposts along the NIH roadmap for reengineering clinical research: Lessons from the clinical research networks initiative. Arch Intern Med. 2008 Sep 22;168(17):1919–25. - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous