Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Jul;53(7):1258-69.
doi: 10.1007/s00125-010-1702-3. Epub 2010 Mar 31.

Is the ADA/EASD algorithm for the management of type 2 diabetes (January 2009) based on evidence or opinion? A critical analysis

G Schernthaner  1 , A H Barnett, D J Betteridge, R Carmena, A Ceriello, B Charbonnel, M Hanefeld, R Lehmann, M T Malecki, R Nesto, V Pirags, A Scheen, J Seufert, A Sjohölm, A Tsatsoulis, R DeFronzo
Affiliations

Is the ADA/EASD algorithm for the management of type 2 diabetes (January 2009) based on evidence or opinion? A critical analysis

G Schernthaner et al. Diabetologia. 2010 Jul.

Erratum in

  • Diabetologia. 2010 Aug;53(8):1813

Abstract

The ADA and the EASD recently published a consensus statement for the medical management of hyperglycaemia in patients with type 2 diabetes. The authors advocate initial treatment with metformin monotherapy and lifestyle modification, followed by addition of basal insulin or a sulfonylurea if glycaemic goals are not met (tier 1 recommendations). All other glucose-lowering therapies are relegated to a secondary (tier 2) status and only recommended for selected clinical settings. In our view, this algorithm does not offer physicians and patients the appropriate selection of options to individualise and optimise care with a view to sustained control of blood glucose and reduction both of diabetes complications and cardiovascular risk. This paper critically assesses the basis of the ADA/EASD algorithm and the resulting tiers of treatment options.

PubMed Disclaimer

Comment in

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Nathan DM, Buse JB, Davidson MB, et al. Management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia. 2006;49:1711–1721. doi: 10.1007/s00125-006-0316-2. - DOI - PubMed
    1. Nathan DM, Buse JB, Davidson MB, et al. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy. A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia. 2009;52:17–30. doi: 10.1007/s00125-008-1157-y. - DOI - PubMed
    1. American Diabetes Association Clinical practice recommendations 2008. Diabetes Care. 2008;31:S1–S2. doi: 10.2337/dc08-S001. - DOI - PubMed
    1. Schünemann HJ, Fretheim A, Oxman AD, WHO Advisory Committee on Health Research Improving the use of research evidence in guideline development: 1. Guidelines for guidelines. Health Res Policy Syst. 2006;4:13. doi: 10.1186/1478-4505-4-13. - DOI - PMC - PubMed
    1. Turner T, Misso M, Harris C, Green S. Development of evidence-based clinical practice guidelines (CPGs): comparing approaches. Implement Sci. 2008;3:45. doi: 10.1186/1748-5908-3-45. - DOI - PMC - PubMed

Substances