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Case Reports
. 2010 Feb;99(2):311-5.
doi: 10.1111/j.1651-2227.2009.00466.x.

Vincristine, an efficacious alternative for diffuse neonatal haemangiomatosis

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Case Reports

Vincristine, an efficacious alternative for diffuse neonatal haemangiomatosis

S Pérez-Valle et al. Acta Paediatr. 2010 Feb.

Abstract

Diffuse neonatal haemangiomatosis (DNH) is an uncommon condition characterized by multiple cutaneous and visceral haemangiomas frequently causing severe complications. Corticosteroids constitute the first therapeutic line; however, when they fail, other alternatives are available, provided possible side effects are closely monitored during and after treatment. We present a case of life-threatening DNH, non-responsive to corticosteroids, successfully treated with Vincristine with minor side effects. We conclude that Vincristine is a valid alternative in corticosteroid-resistant DNH.

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