Vincristine, an efficacious alternative for diffuse neonatal haemangiomatosis
- PMID: 20353500
- DOI: 10.1111/j.1651-2227.2009.00466.x
Vincristine, an efficacious alternative for diffuse neonatal haemangiomatosis
Abstract
Diffuse neonatal haemangiomatosis (DNH) is an uncommon condition characterized by multiple cutaneous and visceral haemangiomas frequently causing severe complications. Corticosteroids constitute the first therapeutic line; however, when they fail, other alternatives are available, provided possible side effects are closely monitored during and after treatment. We present a case of life-threatening DNH, non-responsive to corticosteroids, successfully treated with Vincristine with minor side effects. We conclude that Vincristine is a valid alternative in corticosteroid-resistant DNH.
Similar articles
-
Diffuse Neonatal Hemangiomatosis: report of 5 cases.J Med Assoc Thai. 2006 Aug;89(8):1297-303. J Med Assoc Thai. 2006. PMID: 17048444
-
[Vincristine treatment for function- and life-threatening infantile hemangioma].Arch Pediatr. 2004 Feb;11(2):99-107. doi: 10.1016/j.arcped.2003.10.014. Arch Pediatr. 2004. PMID: 14761730 French.
-
Diffuse infantile hepatic hemangiomas: a report of four cases successfully managed with medical therapy.Pediatr Dermatol. 2011 May-Jun;28(3):267-75. doi: 10.1111/j.1525-1470.2011.01421.x. Epub 2011 Apr 26. Pediatr Dermatol. 2011. PMID: 21517953
-
Vincristine as a treatment for a large haemangioma threatening vital functions.Br J Plast Surg. 2004 Mar;57(2):168-71. doi: 10.1016/j.bjps.2003.11.003. Br J Plast Surg. 2004. PMID: 15037175 Review.
-
Multiple cutaneous and hepatic infantile hemangiomas having a successful response to propranolol as monotherapy at neonatal period.G Ital Dermatol Venereol. 2013 Oct;148(5):525-30. G Ital Dermatol Venereol. 2013. PMID: 24005146 Review.
Cited by
-
Educational paper: therapy of infantile haemangioma--history and current state (part II).Eur J Pediatr. 2015 Feb;174(2):259-66. doi: 10.1007/s00431-014-2404-5. Epub 2014 Sep 3. Eur J Pediatr. 2015. PMID: 25178895 Review.
-
Infantile Periocular Hemangioma.J Ophthalmic Vis Res. 2017 Apr-Jun;12(2):205-211. doi: 10.4103/jovr.jovr_66_17. J Ophthalmic Vis Res. 2017. PMID: 28540013 Free PMC article. Review.
-
Nanotechnology in Infantile Hemangioma Management.J Pediatr Pharmacol Ther. 2025 Feb;30(1):27-46. doi: 10.5863/1551-6776-30.1.27. Epub 2025 Feb 10. J Pediatr Pharmacol Ther. 2025. PMID: 39935564 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical