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. 2010 Apr 27;102(9):1397-9.
doi: 10.1038/sj.bjc.6605624. Epub 2010 Mar 30.

Cancer risk in patients hospitalised for Graves' disease: a population-based cohort study in Sweden

X Shu  1 , J Ji, X Li, J Sundquist, K Sundquist, K Hemminki
Affiliations

Cancer risk in patients hospitalised for Graves' disease: a population-based cohort study in Sweden

X Shu et al. Br J Cancer. .

Abstract

Background: The possibility of an association of Graves' disease (GD) with subsequent cancers raised by certain studies.

Methods: Using a database on 18 156 hospitalised GD patients, subsequent cancers were ascertained.

Results: Increased risks of thyroid and parathyroid tumours were limited to the early follow-up period, which is probably a surveillance bias. Cancer sites with observed excess included the mouth and breast, in contrast to decreased risks of colon cancer, melanoma and non-Hodgkin's lymphoma.

Conclusion: Increased subsequent cancers in GD patients appeared to be balanced by decreased risks at other sites; chance cannot be excluded.

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Conflict of interest statement

The authors declare no conflict of interest.

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