Review
doi: 10.1038/ki.2010.5.
Urinary liver fatty acid-binding protein: another novel biomarker of acute kidney injury
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- PMID: 20354549
- DOI: 10.1038/ki.2010.5
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Review
Urinary liver fatty acid-binding protein: another novel biomarker of acute kidney injury
Kidney Int.
2010 Apr.
Free article
Abstract
Liver fatty acid-binding protein (L-FABP) binds selectively to intracellular free unsaturated fatty acids and lipid peroxidation products during hypoxic tissue injury. Urinary L-FABP is a potential biomarker for the detection and assessment of acute kidney injury (AKI). Ferguson et al. have demonstrated in a cross-sectional study that urinary L-FABP is an excellent biomarker of AKI and may be useful in predicting dialysis-free survival. This study did not assess utility for early diagnosis of AKI.
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