Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2010 Apr 7;16(13):1680-2.
doi: 10.3748/wjg.v16.i13.1680.

Upper gastrointestinal hemorrhage caused by superwarfarin poisoning

Shu Lei Zhao  1 , Peng Li, Ming Ji, Ye Zong, Shu Tian Zhang
Affiliations
Case Reports

Upper gastrointestinal hemorrhage caused by superwarfarin poisoning

Shu Lei Zhao et al. World J Gastroenterol. .

Abstract

Superwarfarins are a class of rodenticides. Gastrointestinal hemorrhage is a fatal complication of superwarfarin poisoning, requiring immediate treatment. Here, we report a 55-year-old woman with tardive upper gastrointestinal hemorrhage caused by superwarfarin poisoning after endoscopic cold mucosal biopsy.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Initial esophagogastroduodenoscopy (EGD) demonstrating normal esophageal mucosa (A) and erosion lesions scattering in the stomach (B).
Figure 2
Figure 2
Second EGD showing submucosal congestion in the esophagus (A), active bleeding in the original biopsy sites (B), and titanium clips used for hemostasis (C).
Figure 3
Figure 3
Final EGD showing the absorbed esophageal submucosal congestion (A) and bleeding in the stomach with titanium clips in good condition (B).
Figure 4
Figure 4
Plain radiography (A) and CT scanning (B) revealing 5 titanium clips in the stomach (arrows).
See this image and copyright information in PMC

References

    1. Laposata M, Van Cott EM, Lev MH. Case records of the Massachusetts General Hospital. Case 1-2007. A 40-year-old woman with epistaxis, hematemesis, and altered mental status. N Engl J Med. 2007;356:174–182. - PubMed
    1. Pavlu J, Harrington DJ, Voong K, Savidge GF, Jan-Mohamed R, Kaczmarski R. Superwarfarin poisoning. Lancet. 2005;365:628. - PubMed
    1. Bruno GR, Howland MA, McMeeking A, Hoffman RS. Long-acting anticoagulant overdose: brodifacoum kinetics and optimal vitamin K dosing. Ann Emerg Med. 2000;36:262–267. - PubMed
    1. Chua JD, Friedenberg WR. Superwarfarin poisoning. Arch Intern Med. 1998;158:1929–1932. - PubMed
    1. Watson WA, Litovitz TL, Rodgers GC Jr, Klein-Schwartz W, Reid N, Youniss J, Flanagan A, Wruk KM. 2004 Annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med. 2005;23:589–666. - PubMed

Publication types