Prevalence of IgG antibodies against West Nile virus in blood donors during the 2003 outbreak in Tunisia
- PMID: 20356614
- DOI: 10.1016/j.trstmh.2010.03.001
Prevalence of IgG antibodies against West Nile virus in blood donors during the 2003 outbreak in Tunisia
Abstract
This study aimed to evaluate the prevalence of anti-West Nile virus (WNV) IgG among two populations of Tunisian blood donors living in areas where human outbreaks of WNV have occurred. Cohorts A (Monastir) and B (Mahdia) included 742 and 102 blood donors respectively. Sera were tested by IgG ELISA test and results were confirmed by PRNT test. WNV neutralizing antibodies were detected in 32 (4.3%) and in 14 (13.7%) sera in cohorts A and B respectively. The prevalence of anti-WNV IgG was significantly higher in cohort B than in cohort A (P<0.001) and was significantly lower in females than in males (P<0.001).
Copyright 2010 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
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