doi: 10.1016/j.diagmicrobio.2010.02.002.
Epub 2010 Mar 31.
D225G mutation in the hemagglutinin protein found in 3 severe cases of 2009 pandemic influenza A (H1N1) in Spain
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- PMID: 20356695
- DOI: 10.1016/j.diagmicrobio.2010.02.002
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D225G mutation in the hemagglutinin protein found in 3 severe cases of 2009 pandemic influenza A (H1N1) in Spain
Diagn Microbiol Infect Dis.
2010 Jun.
Abstract
From 27 April to 16 December 2009, we analyzed the hemagglutinin gene sequence of 2009 pandemic influenza A (H1N1) virus in 189 respiratory specimens. We only found the D225G mutation in 3 severe cases. However, it was not found in samples from other cases with or without clinical criteria of severity. The biologic significance of this mutation remains still unclear.
Copyright 2010 Elsevier Inc. All rights reserved.
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