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Randomized Controlled Trial
. 2010 Jul;33(7):1457-9.
doi: 10.2337/dc09-2336. Epub 2010 Mar 31.

Prevention of gestational diabetes: feasibility issues for an exercise intervention in obese pregnant women

Leonie K Callaway  1 , Paul B Colditz, Nuala M Byrne, Barbara E Lingwood, Ingrid J Rowlands, Katie Foxcroft, H David McIntyre; BAMBINO Group
Collaborators, Affiliations
Randomized Controlled Trial

Prevention of gestational diabetes: feasibility issues for an exercise intervention in obese pregnant women

Leonie K Callaway et al. Diabetes Care. 2010 Jul.

Abstract

Objective: To examine the feasibility of an individualized exercise program to prevent gestational diabetes mellitus (GDM) in obese pregnant women.

Research design and methods: The study was a pilot randomized controlled trial with obese pregnant women (intervention group, individualized exercise program [n = 25]; control group, usual care [n = 25]). Average weekly energy expenditure (MET hours per week and kilocalories per week) of exercise-specific activity was assessed during pregnancy using the Pregnancy Physical Activity Questionnaire. Fasting glucose and insulin and homeostasis model assessment of insulin resistance (HOMA-IR) were assessed at baseline and 20, 28, and 36 weeks' gestation.

Results: Of the women in the intervention group, 16 of 22 (73%) achieved more than 900 kcal/week of exercise-based activity at 28 weeks compared with 8 of 19 women in the control group (42%), P = 0.047. However, insulin resistance (HOMA-IR) did not differ between the groups.

Conclusion: This intervention was feasible and prompted a modest increase in physical activity. However, we are not confident that this intervention would be sufficient to prevent GDM.

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References

    1. Chu SY, Callaghan WM, Kim SY, Schmid CH, Lau J, England LJ, Dietz PM: Maternal obesity and risk of gestational diabetes mellitus. Diabetes Care 2007; 30: 2070–2076 - PubMed
    1. Guelinckx I, Devlieger R, Mullie P, Vansant G: Effect of lifestyle intervention on dietary habits, physical activity, and gestational weight gain in obese pregnant women: a randomized controlled trial. Am J Clin Nutr 2009; 91: 373–380 - PubMed
    1. Colley RC, Hills AP, O'Moore-Sullivan TM, Hickman IJ, Prins JB, Byrne NM: Variability in adherence to an unsupervised exercise prescription in obese women. Int J Obes (Lond) 2008; 32: 837–844 - PubMed
    1. Lindström J, Louheranta A, Mannelin M, Rastas M, Salminen V, Eriksson J, Uusitupa M, Tuomilehto J. Finnish Diabetes Prevention Study Group. The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3-year results on diet and physical activity. Diabetes Care 2003; 26: 3230–3236 - PubMed
    1. Glasgow RE, Lichtenstein E, Marcus AC: Why don't we see more translation of health promotion research to practice? Rethinking the efficacy-to-effectiveness transition. Am J Public Health 2003; 93: 1261–1267 - PMC - PubMed

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