Review
doi: 10.1146/annurev.me.42.020191.002105.
Unusual forms of insulin resistance
Affiliations
- PMID: 2035982
- DOI: 10.1146/annurev.me.42.020191.002105
Item in Clipboard
Review
Unusual forms of insulin resistance
Annu Rev Med.
1991.
Abstract
Insulin resistance is an important feature in the pathogenesis of non-insulin-dependent diabetes mellitus. Some rare patients have syndromes associated with a severe form of insulin resistance, usually involving acanthosis nigricans and, in premenopausal females, hyperandrogenism. This review discusses two of the causes of insulin resistance: mutations in the insulin receptor gene and autoantibodies directed against the insulin receptor.
Similar articles
-
[Syndromes of severe insulin resistance].Nihon Rinsho. 1999 Mar;57(3):617-21. Nihon Rinsho. 1999. PMID: 10199143 Review. Japanese.
-
[HAIR-AN syndrome].Nihon Rinsho. 1994 Oct;52(10):2648-52. Nihon Rinsho. 1994. PMID: 7983793 Review. Japanese.
-
[Insulin resistance: from clinical diagnosis to molecular genetics. Implications in diabetes mellitus].Bull Acad Natl Med. 1999;183(9):1761-75; discussion 1775-7. Bull Acad Natl Med. 1999. PMID: 10987057 Review. French.
-
[Mutations in the insulin receptor gene].Nihon Rinsho. 2002 Jul;60 Suppl 7:642-7. Nihon Rinsho. 2002. PMID: 12238112 Review. Japanese. No abstract available.
-
[Amenorrhea, insulin resistance and acanthosis nigricans. A hyperandrogenic and a normoandrogenic clinical forms].Rev Med Chil. 1993 Feb;121(2):170-5. Rev Med Chil. 1993. PMID: 8303114 Spanish.
Cited by
-
The Insulin Receptor: An Important Target for the Development of Novel Medicines and Pesticides.Int J Mol Sci. 2022 Jul 14;23(14):7793. doi: 10.3390/ijms23147793. Int J Mol Sci. 2022. PMID: 35887136 Free PMC article. Review.
-
Insulin resistance due to mutations of the insulin receptor gene: an overview.J Endocrinol Invest. 1992 Dec;15(11):857-64. doi: 10.1007/BF03348820. J Endocrinol Invest. 1992. PMID: 1291599 Review. No abstract available.
-
Insulin Receptor Isoforms in Physiology and Disease: An Updated View.Endocr Rev. 2017 Oct 1;38(5):379-431. doi: 10.1210/er.2017-00073. Endocr Rev. 2017. PMID: 28973479 Free PMC article. Review.
-
Transcriptional Regulation of Glucose Metabolism: The Emerging Role of the HMGA1 Chromatin Factor.Front Endocrinol (Lausanne). 2018 Jul 3;9:357. doi: 10.3389/fendo.2018.00357. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 30034366 Free PMC article. Review.
-
Immunosuppressive Therapy in Treatment of Refractory Hypoglycemia in Type B Insulin Resistance: A Case Report.J Endocr Soc. 2017 Nov 3;1(12):1435-1439. doi: 10.1210/js.2017-00292. eCollection 2017 Dec 1. J Endocr Soc. 2017. PMID: 29264467 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
