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. 2010 Mar 30;7(3):e1000245.
doi: 10.1371/journal.pmed.1000245.

Can animal models of disease reliably inform human studies?

H Bart van der Worp  1 , David W Howells, Emily S Sena, Michelle J Porritt, Sarah Rewell, Victoria O'Collins, Malcolm R Macleod
Affiliations

Can animal models of disease reliably inform human studies?

H Bart van der Worp et al. PLoS Med. .

Abstract

H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials.

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Conflict of interest statement

Malcolm R. MacLeod is on the Editorial Board of PLoS Medicine.

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