Researching genetic versus nongenetic determinants of disease: a comparison and proposed unification
- PMID: 20368180
- DOI: 10.1126/scitranslmed.3000247
Researching genetic versus nongenetic determinants of disease: a comparison and proposed unification
Abstract
Research standards deviate in genetic versus nongenetic epidemiology. Besides some immutable differences, such as the correlation pattern between variables, these divergent research standards can converge considerably. Current research designs that dissociate genetic and nongenetic measurements are reaching their limits. Studies are needed that massively measure genotypes, nongenetic exposures, and outcomes concurrently.
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