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Practice Guideline
. 2010;14(2):R52.
doi: 10.1186/cc8943. Epub 2010 Apr 6.

Management of bleeding following major trauma: an updated European guideline

Rolf Rossaint  1 , Bertil Bouillon, Vladimir Cerny, Timothy J Coats, Jacques Duranteau, Enrique Fernández-Mondéjar, Beverley J Hunt, Radko Komadina, Giuseppe Nardi, Edmund Neugebauer, Yves Ozier, Louis Riddez, Arthur Schultz, Philip F Stahel, Jean-Louis Vincent, Donat R Spahn; Task Force for Advanced Bleeding Care in Trauma
Affiliations
Practice Guideline

Management of bleeding following major trauma: an updated European guideline

Rolf Rossaint et al. Crit Care. 2010.

Abstract

Introduction: Evidence-based recommendations are needed to guide the acute management of the bleeding trauma patient, which when implemented may improve patient outcomes.

Methods: The multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed in 2005 with the aim of developing a guideline for the management of bleeding following severe injury. This document presents an updated version of the guideline published by the group in 2007. Recommendations were formulated using a nominal group process, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) hierarchy of evidence and based on a systematic review of published literature.

Results: Key changes encompassed in this version of the guideline include new recommendations on coagulation support and monitoring and the appropriate use of local haemostatic measures, tourniquets, calcium and desmopressin in the bleeding trauma patient. The remaining recommendations have been reevaluated and graded based on literature published since the last edition of the guideline. Consideration was also given to changes in clinical practice that have taken place during this time period as a result of both new evidence and changes in the general availability of relevant agents and technologies.

Conclusions: This guideline provides an evidence-based multidisciplinary approach to the management of critically injured bleeding trauma patients.

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Figures

Figure 1
Figure 1
Flow chart of treatment modalities for the bleeding trauma patient discussed in this guideline. APTT: activated partial thromboplastin time; ASS: acetylsalicylsalicylic acid; CT: computed tomography; FAST: focused abdominal sonography for trauma; Hb: haemoglobin; INR: international normalised ratio.
See this image and copyright information in PMC

Comment in

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