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. 2010 Jul;118(7):1021-6.
doi: 10.1289/ehp.0901232. Epub 2010 Mar 22.

Childhood incident asthma and traffic-related air pollution at home and school

Rob McConnell  1 , Talat Islam, Ketan Shankardass, Michael Jerrett, Fred Lurmann, Frank Gilliland, Jim Gauderman, Ed Avol, Nino Künzli, Ling Yao, John Peters, Kiros Berhane
Affiliations

Childhood incident asthma and traffic-related air pollution at home and school

Rob McConnell et al. Environ Health Perspect. 2010 Jul.

Abstract

Background: Traffic-related air pollution has been associated with adverse cardiorespiratory effects, including increased asthma prevalence. However, there has been little study of effects of traffic exposure at school on new-onset asthma.

Objectives: We evaluated the relationship of new-onset asthma with traffic-related pollution near homes and schools.

Methods: Parent-reported physician diagnosis of new-onset asthma (n = 120) was identified during 3 years of follow-up of a cohort of 2,497 kindergarten and first-grade children who were asthma- and wheezing-free at study entry into the Southern California Children's Health Study. We assessed traffic-related pollution exposure based on a line source dispersion model of traffic volume, distance from home and school, and local meteorology. Regional ambient ozone, nitrogen dioxide (NO(2)), and particulate matter were measured continuously at one central site monitor in each of 13 study communities. Hazard ratios (HRs) for new-onset asthma were scaled to the range of ambient central site pollutants and to the residential interquartile range for each traffic exposure metric.

Results: Asthma risk increased with modeled traffic-related pollution exposure from roadways near homes [HR 1.51; 95% confidence interval (CI), 1.25-1.82] and near schools (HR 1.45; 95% CI, 1.06-1.98). Ambient NO(2) measured at a central site in each community was also associated with increased risk (HR 2.18; 95% CI, 1.18-4.01). In models with both NO(2) and modeled traffic exposures, there were independent associations of asthma with traffic-related pollution at school and home, whereas the estimate for NO(2) was attenuated (HR 1.37; 95% CI, 0.69-2.71).

Conclusions: Traffic-related pollution exposure at school and homes may both contribute to the development of asthma.

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References

    1. Appatova AS, Ryan PH, Lemasters GK, Gruinshpun SA. Proximal exposure of public schools and students to major roadways: a nationwide US survey. J Environ Plann Manage. 2008;51:631–646.
    1. Asher MI, Keil U, Anderson HR, Beasley R, Crane J, Martinez F, et al. International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J. 1995;8(3):483–491. - PubMed
    1. Benson P. Caline4—A Dispersion Model for Predicting Air Pollution Concentration Near Roadways. Sacramento: California Department of Transportation, Office of Transportation Laboratory; 1989.
    1. Braman SS. The global burden of asthma. Chest. 2006;130(suppl 1):4S–12S. - PubMed
    1. Brauer M, Hoek G, Smit HA, de Jongste JC, Gerritsen J, Postma DS, et al. Air pollution and development of asthma, allergy and infections in a birth cohort. Eur Respir J. 2007;29(5):879–888. - PubMed

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