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. 2010 Sep;267(9):1437-44.
doi: 10.1007/s00405-010-1244-9. Epub 2010 Apr 7.

Early and long-term morbidity after total laryngopharyngectomy

Stijn Keereweer  1 , Johannes H W de Wilt, Aniel Sewnaik, Cees A Meeuwis, Hugo W Tilanus, Jeroen D F Kerrebijn
Affiliations

Early and long-term morbidity after total laryngopharyngectomy

Stijn Keereweer et al. Eur Arch Otorhinolaryngol. 2010 Sep.

Abstract

To determine the early and long-term morbidity of patients treated with a total laryngopharyngectomy and reconstruction using a jejunum interposition or gastric pull-up procedure. It is a retrospective study; and it is conducted in tertiairy referral center. Sixty-three patients were included in whom 70 reconstructions were performed (51 jejunum interpositions and 19 gastric pull-up procedures) between 1990 and 2007. The studied parameters were success rate of the reconstruction, early and long-term complication rate, and functional outcome including quality of life. Subjective quality of life analysis was determined by two questionnaires: the EORTC Quality of Life Questionnaire (QLQ)-C30 Dutch version 3.0, and the EORTC-Head and Neck (H & N 35). The success rates were 84 and 74%, respectively. The procedures were associated with a high complication rate (63% after jejunum interposition and 89% after gastric pull-up), and a lengthy rehabilitation. Surviving patients were found to have a good long-term quality of life. Complete oral intake was achieved in 97%, and speech rehabilitation in 95%. These procedures are associated with significant morbidity, high complication rates, lengthy rehabilitation, but a good long-term quality of life.

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Figures

Fig. 1
Fig. 1
Success rate of jejunum interposition and gastric pull-up, showing 70 procedures performed in 63 patients
See this image and copyright information in PMC

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