Adipose tissue lipolysis revisited (again!): lactate involvement in insulin antilipolytic action
- PMID: 20374952
- DOI: 10.1016/j.cmet.2010.03.003
Adipose tissue lipolysis revisited (again!): lactate involvement in insulin antilipolytic action
Abstract
Lactate is produced from glucose by adipose tissue. In this issue of Cell Metabolism, Ahmed et al. (2010) show that the metabolite is involved in the antilipolytic effect of insulin, providing a new link between fat and carbohydrate metabolism.
2010 Elsevier Inc. All rights reserved.
Comment on
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An autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81.Cell Metab. 2010 Apr 7;11(4):311-9. doi: 10.1016/j.cmet.2010.02.012. Cell Metab. 2010. PMID: 20374963
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